Why mixed consumption is so dangerous:

Written by: Marvin Benthien



Time to read 5 min

In the world of psychoactive and psychedelic substances, it is always better to be safe than sorry. Individual consumption is already associated with certain dangers and risks, which can increase with mixed consumption. But what exactly is mixed use? As the name suggests, it is the use of several drugs in combination. Each drug has its own effects on the body and can, for example, raise - or lower - blood pressure. If several drugs with similar physiological effects are consumed at the same time, this is tantamount to an overdose. Mixed consumption is therefore responsible for most fatal cases after taking party drugs. But which drugs are particularly harmful and which ones have negligible interactions? Below we have summarized which drugs affect each other and how, what exactly happens with mixed consumption and why mixed consumption is so dangerous.

Disclaimer for our readers: This is an informative lifestyle blog that makes no claim to medical or scientific completeness. We would like to emphasize that this blog is against the illegal use and glorification of drugs in general. Our aim is to provide factual information and awareness-raising content within a responsible framework. It is important to be fully aware of the legal and health consequences associated with the use of (psychoactive) substances. We believe in the importance of informed choices and encourage a reflective approach to legal alternatives to current health issues. The safety and health of our readers is our top priority.

Mixing Mushrooms and alcohol:

The mixed consumption of mushrooms and alcohol can be quite dangerous and requires special caution. Mushrooms on their own can produce strong hallucinogenic effects that influence perception and thinking. If alcohol is consumed at the same time, the coordination problems and nausea that can be triggered by mushrooms are potentially exacerbated.

Furthermore, the combination of alcohol and mushrooms can significantly increase the risk of anxiety, panic attacks and paranoia. These psychological effects can lead to unpredictable behavior and impair self-control. It is also important to mention that alcohol enhances the effects of mushrooms, which can cause you to unintentionally consume too much psilocybin. It is therefore recommended not to consume these two substances together.

Mixing LSD and alcohol:

Mixed consumption of LSD and alcohol is also extremely risky and can have serious health consequences. LSD is a potent hallucinogen that strongly alters perception, thoughts and emotions. Alcohol can unpredictably intensify or weaken the effects of LSD, which can lead to dangerous, disorienting experiences.

The combination of LSD and alcohol also increases the risk of anxiety, panic attacks and paranoia. Additionally, alcohol impairs one's judgment and ability to recognize danger, which increases the risk of accidents or injuries. It is advisable not to consume LSD and alcohol together.

Mixing LSD and mushrooms:

The simultaneous consumption of LSD and mushrooms, such as psilocybin mushrooms, is no less risky. It can have considerable effects on the psyche and health. Both substances are powerful hallucinogens and act in a similar way in the brain, allowing the active ingredients to interact with each other. Mixed consumption can lead to extremely intense hallucinations and psychological stress.

It is important to note that the effects of LSD and mushrooms can vary greatly and depend on many factors, including individual tolerance and dosage. It is almost impossible to predict what can happen with uncontrolled mixed use. Therefore, it is strongly recommended not to consume LSD and mushrooms together.

Combining different psychedelics? Usually not a good idea.

Mixing LSD and cannabis:

Both LSD and cannabis are psychoactive and affect the brain in different ways. When combined, they can amplify each other - which can lead to an overwhelming experience.

Cannabis can intensify the hallucinogenic effects of psychedelics, leading to more intense visual and auditory hallucinations. This can make the spiritual journey on LSD even more uncontrollable (than it already is) and trigger anxiety and paranoia. The combination can also increase heart rate and affect blood pressure, providing a fertile ground for further physical ailments.

Mixed use of LSD and cannabis is therefore insanely risky and depends on many factors, including individual tolerance and dosage. It is strongly advised not to combine these substances.

Mixing LSD and MDMA:

LSD is a hallucinogen that can cause strong visual and emotional changes. MDMA, on the other hand, is a stimulant with a euphoric effect. The combination of these two drugs can lead to intense hallucinations, accompanied by increased energy levels and an increased risk of cardiovascular problems.

Similarly, the mixed use of LSD and MDMA can lead to a prolonged and more intense crash (after the effects wear off), accompanied by severe malaise and mental disorders. These two substances should definitely not be consumed at the same time.

Mixing mushrooms and MDMA:

The mixed use of MDMA and mushrooms, such as psilocybin mushrooms, is a rather risky combination. MDMA is a stimulant that can induce states of heightened euphoria and empathy, while psilocybin mushrooms have strong hallucinogenic effects. The effects of MDMA and mushrooms can reinforce each other and lead to unpleasant psychological and emotional experiences. This can lead to anxiety, paranoia and an altered sense of reality. Mixed use can also increase the risk of dehydration and overheating, as MDMA increases body temperature. Taking MDMA and mushrooms at the same time should be avoided.

Mixing MDMA and cannabis:

Mixed use of MDMA and weed is a common practice, but it is not without risks. Some people experience a more intense euphoria, while others may experience a diminished effect from MDMA due to the sedative effects of cannabis. This can lead to miscalculations and risks, as the dose and reaction are difficult to predict.

Additionally, mixed use can cause anxiety, paranoia and general mental confusion. It is important to exercise caution and be aware that the combination of MDMA and cannabis is not suitable for everyone.

Always be careful when combining cannabis with psychedelics.

Mixing MDMA and 2C-B:

Mixed use of MDMA and 2C-B, a synthetic psychedelic substance, is extremely risky and requires particular caution. MDMA is known for its stimulant and empathogenic effects, while 2C-B has a strong psychedelic effect.

The effects of MDMA can mask or intensify those of 2C-B, which can lead to severe psychological distress. Hallucinations, confusion, anxiety and panic attacks can result. Increased dehydration and overheating can also be symptoms. It is not recommended to consume MDMA and 2C-B together.

A slightly different view on mixed consumption

Most discussions about drug use focus mainly on the negative effects and risks associated with mixed use. However, it is also possible to look at the mixed use of drugs from a harm-reduction perspective. Harm reduction is an approach that aims to minimize the risks and harms associated with drug use, rather than abstaining from use altogether.

From this perspective, mixed use could be seen as a step towards safer drug use. Instead of consuming a single dangerous substance in large quantities, some people combine different drugs in smaller amounts to reduce the negative effects of a single intoxicant. This could mean, for example, that someone mixes alcohol with another substance in order to consume less alcohol and thus minimize the risk of alcohol intoxication.

However, it is by no means said that this approach is safe or endorses the use of drugs. The consumption of drugs needs to be well thought out and is always done at one's own risk - whether mixed consumption or not.

Risky and unpredictable - leave the mixing to the DJ.

As described above, the effects of combining different substances are often unpredictable and can sometimes be very severe. This is not only the case for the combinations already mentioned, but also applies to the mixed use of any other substances such as cocaine and speed - and medication. Especially if you take medication regularly or at the time of consumption, it is essential to clarify whether it is compatible with the planned substances. You need to be particularly careful with the dosage to avoid overdosing. Spontaneous and reckless drug experiments are not recommended under any circumstances.

An informed approach to drugs and open communication about the consequences of mixed consumption are crucial to protect life and health.