The 1D-LSD successor: 1S-LSD – what can the new derivative do?

Der 1D-LSD-Nachfolger: 1S-LSD – was kann das neue Derivat? - Psychedelics & Retreats für dein Wohlbefinden | MODERNmind

Psychedelic research is constantly evolving. A new star in this science is 1S LSD, the successor to 1D LSD, 1T LSD, 1P LSD and other LSD derivatives. But what makes the new 1S LSD so special? On June 21, 2024, the fifth regulation amending the appendix to the New Psychoactive Substances Act was passed by the legislature, closing a legal loophole and prohibiting the trade in 1D LSD. In the midst of these regulatory changes, the 1S LSD successor appears and offers new opportunities for research and application.

What exactly is 1S LSD?

1S LSD stands for 1-trimethylsilyl-propionyl-lysergic acid diethylamide hemi-D-tartrate. The structure of this molecule contains a trimethylsilyl group (TMS) that is bound to a propionyl group, which in turn is attached to the lysergic acid diethylamide molecule. The special thing about this successor is that it does not fall under the New Psychoactive Substances Act (NpSG) and is therefore legally available for research purposes. Experienced users report that its effect is very similar to that of 1cp LSD. This derivative is considered a prodrug, an inactive or less active form of a substance that is converted into its active form after administration.

What is particularly important for researchers is that the structure shows no noticeable differences in the way the molecule of the 1D LSD successor works compared to the previous LSD derivatives. This means that experiments such as those with the 1DLSD dosage can be carried out and produce comparable results.

The 1D LSD ban – what’s really behind it

The new regulation from the Federal Ministry of Health prohibits the trade in 1T LSD and 1D LSD, while possession remains legal. This apparent paradox can be traced back to the regulatory conditions of the NpSG. LSD derivatives such as 1T LSD and 1D LSD are enjoying increasing popularity in research. Their effects on the brain and consciousness are the subject of intensive scientific research. However, their widespread use also brings with it the risk that they could be used uncontrolled and improperly, which poses potential health risks.

What is the purpose of the 1D LSD ban?

The ban on 1D LSD aims to minimise these dangers by restricting trade, thereby limiting access and availability to the wider market. However, by not criminalising possession, it aims to ensure that existing stocks remain accessible for scientific purposes. This approach is typical of the regulation of legal highs, which seeks to balance both the promotion of research and the protection of public health.

1S LSD as a new opportunity for researchers

In this context, the new derivative 1S LSD is gaining importance. It offers researchers a legal alternative for their research. The similar chemical structure to other LSD derivatives makes it possible to research comparable effects on the human brain without the legal restrictions and risks associated with banned substances. It is important to stress that the regulation of legal highs is a complex issue that must take into account both scientific innovation and public safety. The development and use of new substances such as 1S LSD therefore require a balanced approach that allows freedom of research while minimizing potential risks.

The current status: Is 1D LSD still legal or banned?

Possession of 1D LSD and 1T LSD remains legal as long as they are not intended or offered for human consumption. However, trading in the substances is prohibited. This means that selling, passing on or exchanging these substances can result in criminal consequences. If you want to go on a research trip with an LSD derivative, you should avoid 1D LSD from now on.

Instead, 1S LSD is considered a legal successor to 1D LSD. Because the substance is structurally similar to 1D LSD and 1T LSD, but may be subject to fewer legal restrictions, it is seen by some as an attractive alternative for legal purchase and trade.

1D LSD is replaced by 1S LSD

At MODERNmind we now offer the new derivative 1S LSD as a successor to 1D LSD. You can order our products discreetly and easily in our online shop as usual. Our selection still includes the LSD microdosing kit and high-dosing LSD tablets, now only with 1S LSD. If you still own MODERNmind products based on 1T LSD or 1D LSD, you don't need to worry: possession remains legal. If you need supplies for your personal research, you can easily switch from 1D LSD to 1S LSD.


However, it is important to stress that the legal regulations regarding psychoactive substances can vary greatly and are subject to constant change. Researchers who wish to work with 1D LSD, 1T LSD or its successor 1S LSD should therefore always pay attention to the current laws and regulations.

1S LSD vs. 1D LSD: The effects in comparison

The differences and similarities between the effects of 1D LSD and 1S LSD provide exciting insights into psychedelic research. 1D LSD can induce powerful psychedelic effects, including visual hallucinations, altered perception, and intense emotional experiences. The intensity and duration of these effects can vary greatly depending on the dosage and the individual sensitivity of the user. The new 1S LSD derivative, according to early reports, shows similar psychoactive effects to 1D LSD and even classic LSD. This includes visual and auditory changes as well as heightened emotional and sensory perception.

1D LSD and 1S LSD in comparison

1S LSD and 1D LSD: possible applications

Since the chemical structure of 1S LSD and 1D LSD is similar, they both have similar effects on the human body. However, reports from users confirm that 1S LSD provides slightly more intense visual impressions. Therefore, its effect is more similar to the original LSD than 1D LSD. The latter is said to have a gentler and more relaxing effect. Since 1S LSD is the legal variant, we would like to introduce you to its possible uses. The use for microdosing is particularly interesting here. In this case, only a small amount of the active ingredient is taken over a longer period of time. This means that the positive effects can be used in everyday life without experiencing an LSD trip:

  • Greater serenity: 1S LSD influences the serotonin balance in the human brain. This neurotransmitter ensures happiness, sleep and appetite. 1S LSD activates the serotonin receptors and thus ensures a more relaxed mood and increased resistance to stress.

  • Increased ability to concentrate: In everyday working life, low doses of 1S LSD can ensure increased concentration. This in turn increases productivity.

  • More creativity: The increased sensory perception caused by 1S LSD ensures an improved creative flow, especially in artistic activities. Whether it is writing, making music or painting, the intensely sensual experiences can trigger a productive “state of flow”.


Researching and comparing the effects of 1S LSD and 1D LSD is crucial to understanding their full potential and expanding their applications in science and potentially medical therapy. The future may continue to bring exciting developments in this field that could revolutionize the way we view psychedelic substances and their potential benefits for human health.

Conclusion: 1D LSD illegal and 1S LSD legal

The new ban on 1D LSD on the market affects all researchers who want to work with the psychoactive substance. If you belong to this group, you can easily switch to 1S LSD. 1S LSD is characterized by very similar psychoactive effects to 1D LSD. This development offers new options to continue conducting your studies without having to circumvent the legal hurdles. Our mission remains the same, too. We want to offer high-quality products and continue to enable experiments in psychedelic research to continue.

With us you can order 1S LSD online legally

At MODERNmind, we see ourselves as pioneers in the provision of high-quality psychedelic substances for research and therefore adapt our product range accordingly. We therefore offer 1S LSD as an alternative to 1D LSD . This allows researchers to continue their work without having to worry about availability and the legal framework. Visit our online store where you can buy LSD legally and discover our other products. With us, you can place your orders safely and discreetly. Our mission is to create the best conditions for your research needs.

Frequently asked questions about 1D LSD and 1S LSD

1S LSD is a new LSD derivative. So it's no wonder that questions arise between the new derivative and the older 1D LSD. If you still have burning questions before you start researching, you'll find them here. We've collected frequently asked questions and answered them clearly for you:

What is the difference between 1D LSD and 1S LSD?

1S LSD is the new LSD derivative. It replaces the older 1D LSD on the market. The chemical structure of the two derivatives is very similar, which is why researchers can continue their studies with the new 1S LSD.

Is 1S LSD legal?

Yes, 1S LSD is legal because it does not yet fall under the New Psychoactive Substances Act (NpSG). Therefore, it can be purchased and taken. If you need to order 1S LSD, you can do so online and discreetly in our shop.

Does 1S LSD work differently than 1D LSD?

Since 1S LSD and 1D LSD are similar in their chemical structure, their effects are not particularly different. However, reports say that 1S LSD produces stronger visual effects, while 1D LSD is said to have a gentler, more relaxing effect.

Is 1D LSD legal?

No, 1D LSD is no longer legal since June 2024. It was included in the New Psychoactive Substances Act (NpSG). However, only trading is prohibited. If you still have leftover stocks, that is not a problem.

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